Neuromuscular and Joint Diseases
Introduction to Neuromuscular and Joint Diseases
Nerves are the wires that connect the control center- the brain and spinal cord- to the rest of our body. When you want to walk across a room, your brain sends that message down your spinal cord to your nerves, which then activates your muscles via a connection called the neuromuscular junction. The nerves, neuromuscular junction and muscles together are referred to as the neuromuscular system. When our nerves, neuromuscular junction or muscles are diseased, it often shows up as weakness, as well as muscle atrophy. Weakness may or may not be associated with activity or heavy exercise. You also may see difficulties in chewing and swallowing.
Joints are the hinges that allow your legs and arms to bend- for instance your knee or elbow. Most often, joint disease is diagnosed and treated by general surgeons. For example arthritis and hip dysplasia are common joint diseases. However, there are some joint diseases that are associated with neurologic disease, or have symptoms very similar to neurologic diseases, so they are covered here. Diseases of the joints often show up as pain or lameness.
Examples of Neuromuscular Disease
Geriatric Onset Laryngeal Paralysis and Polyneuropathy
Neuritis
Nerve Sheath Tumors
Paraneoplastic Neuropathies
Tetanus
Botulism
Facial Nerve Paralysis
Tick Bite Paralysis
Polyradiculoneuritis
Trigeminal Neuritis
Myasthenia Gravis
Polymyositis
Inherited Myopathies
Extraocular Myositis
Masticatory Myositis
Examples of Joint Diseases
Steroid Responsive Meningitis Arteritis
Immune Mediated Polyarthritis
Diagnosis
Diagnosis of neuromuscular diseases can involve a variety of tests. We may recommend testing of the spine, such as an MRI, to look at the origin of the nerves. Imaging of the chest and abdomen may also be recommended to look for diseases in another body system that might affect the muscles and nerves. Some conditions, like Masticatory Myositis or Myasthenia Gravis, have blood tests that can confirm the diagnosis. Some animals will undergo electrodiagnostic testing in which we measure the electrical activity in the muscles and nerves. Finally, some diseases require biopsies of the muscles and nerves.
Diagnosis of joint diseases often requires the collection of joint fluid for culture and analysis. In some instances, other infectious disease testing will also be recommended.
Treatment and Prognosis
Nerve sheath tumors are best treated early. If we can fully remove the tumor at surgery, your pet can be cured. Unfortunately some tumors have already invaded the spinal cord or brain by the time we have diagnosed them, and therefore complete removal is not possible.
What is an Emergency
Unable to stand
Pain not controlled by medications
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