Cefpodoxime (Simplicef®)

Introduction to Cefpodoxime (Simplicef)

Cefpodoxime, marketed under the brand name Simplicef, is an antibiotic used to treat bacterial infections primarily in dogs and cats. It is effective against skin and urinary tract infections and may also be used for treating other conditions like diskospondylitis, an infection of the spine.

Introduction to Cefpodoxime (Simplicef®)

Guidelines for Missed Doses and Changing Medications

If you miss a dose of cefpodoxime, administer it as soon as you remember. However, if it's almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to catch up. If you have any doubts or need to change the medication, consult your veterinarian for advice.

Monitoring and Lab Work

Monitoring the effectiveness of cefpodoxime may require periodic lab tests, such as a white blood cell count or a bacterial culture, to determine if the infection is responding to treatment. If there are any concerns about how your pet is responding to the medication, it's important to consult with your veterinary team.

Potential Side Effects

While cefpodoxime is generally well-tolerated by dogs and cats, like all medications, it can cause side effects. Common gastrointestinal side effects include:

  • Loss of appetite

  • Vomiting

  • Diarrhea

Although rare, some pets may develop drug allergies, skin issues, or experience a decrease in red and white blood cell counts. If you notice any unusual symptoms or side effects in your pet, contact your veterinarian immediately.


Contact Us:

Mon \ Fri: 8:30am - 5:30pm

Sat: by appointment only

Phone: (415)967-3303

Email: frontdesk@remedyvets.com

Request Appointment

New and returning patient appointment request forms