Topiramate (Topamax®)

Introduction to Topiramate

Topiramate (Topimax) is an anticonvulsant medication primarily used to manage and reduce the frequency and severity of seizures in pets. While it can significantly improve seizure control, it is important to note that it may not completely eliminate all seizures.

Skeletal formula of Topiramate

Guidelines for Administration and Medication Management

Administration: Topiramate is typically administered twice daily and can be given with or without food.
Missed Doses: Consistency is crucial in managing seizures, so set reminders to administer medication on time. If you miss a dose, give it as soon as you remember, but if it's close to the next scheduled dose, skip the missed dose and continue as normal.
Refills: Keep track of your medication supply and arrange refills at least one week in advance to avoid interruptions.
Medication Changes: Never stop or alter the dosage without consulting your vet. Seizure medications generally need to be tapered off rather than stopped abruptly.

Monitoring and Lab work

Regular veterinary check-ups are vital when your pet is on seizure medication. It's recommended to have:

Veterinary Visits: Biannual visits to discuss your pet's response to treatment.
Lab Work: Due to the relatively uncommon use of Topiramate in veterinary medicine and potential unknown long-term effects, comprehensive blood work (CBC and Chemistry) and urinalysis are advised every six months.

Possible Side effects

This medication seems to be very well tolerated overall, but is not a commonly used medication. Please contact the medical team with any concerns. The following side effects have been reported.

GI upset including vomiting, diarrhea and inappetance
Drowsiness and incoordination these side effects may lessen with time
Irritability or nervousness
Glaucoma and kidney stones have been reported in people on this medication, but have yet to be reported in dogs and cats.